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. 2020 Oct 22;25(21):4873. doi: 10.3390/molecules25214873

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Monarda essential oils increase [Ca²⁺]_i in HEK transient receptor potential TRPA1 cells. Original representative traces demonstrating the dose-dependent effects of flower essential oil (MEO_Fl) (A) and leaf essential oil (MEO_Lv) (B). Arrows indicate the effects of 5 (#1), 10 (#2), 15 (#3), 20 (#4), and 25 (#5) µg/mL of the oils on [Ca²⁺]_i in HEK rTRPA1 cells. Summarized data for the dose-dependent increase in [Ca²⁺]_i are shown in (C) and (D). The data are represented as mean ± SEM (n = 90 cells) from 3 independent experiments.