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. 2020 Oct 22;25(21):4873. doi: 10.3390/molecules25214873

Table 4.

Relative content of constituent monoterpenes in MEOFl and MEOLv and their effects on [Ca2+]i flux in HEK rTRPA1-transfected cells.

Compound Composition HEK Cells
MEOFl MEOLv rTRPA1 NT
% [Ca2+]i Change
α-Pinene 0.7 0.4 0.054 ± 0.014 0.013 ± 0.002
Camphene 0.1 0.1 0.014 ± 0.004 0.009 ± 0.001
β-Pinene 0.2 0.1 0.012 ± 0.002 0.011 ± 0.001
Sabinene 0.3 0.1 0.029 ± 0.005 0.034 ± 0.004
β-Myrcene 1.4 0.8 0.111 ± 0.003 0.005 ± 0.001
α-Terpinene 3.8 1.7 0.007 ± 0.001 0.006 ± 0.001
(-) Limonene 0.9 0.5 0.008 ± 0.002 0.007 ± 0.001
(+) Limonene - - 0.011 ± 0.002 0.009 ± 0.002
γ-Terpinene 6.8 2.5 0.034 ± 0.005 0.014 ± 0.001
p-Cymene 25.6 13.1 0.071 ± 0.011 0.027 ± 0.001
Terpinolene 0.1 - 0.034 ± 0.007 0.022 ± 0.003
Linalool 0.1 0.1 0.037 ± 0.007 0.002 ± 0.0003
Terpinen-4-ol 1.1 - 0.046 ± 0.007 0.013 ± 0.002
α-Terpineol 0.2 0.1 0.010 ± 0.002 0.004 ± 0.001
Thymol 3.1 3.3 0.849 ± 0.013 0.026 ± 0.002
Carvacrol 45.7 71.5 0.340 ± 0.012 0.061 ± 0.018

Values of [Ca2+]i changes are presented as the mean ± S.E.M. of 3 independent experiments, as described in Materials and Methods. The cells were treated with 100 µM of monoterpene, and [Ca2+]i was monitored, as described. NT, nontransfected HEK cells.