Table 3.

Clues for metabolic based autistic features

Coexist symptoms	Lab Tests	Diagnosis
ASD+Microcephaly	HPLC of AA	PKU,Serin deficiency,
ASD +Abnormal Movements+Epilepsy	Creatin Pannel	Cerebral creatin Deficiency syndromes
Distinct Syndromic appearence	Cholestrol pannel	Smith lemli opitz
Self Mutilation	Uric acid	Lesh nyhan syndrome
Coarse Facies +ASD	Urin Mucopolysacharides	Sanfilippo
ASD+acidosis	Biotine panel Urinary organic acids Lactat	Biotinidase deficienct Organic academia Mitochondrial disorders Lactate pathway
Macrocytic anemia+ASD	B12,Folate	MMA Homocystinuria Vitamins deficiency