Table 1.
Single nucleotide polymorphisms associated with periodontitis.
| rsID | Locus | Nearest gene | EA | NEA | EAF | OR (95% CI) | p-value | PVE (%) | Reference |
|---|---|---|---|---|---|---|---|---|---|
| rs1537415 | 9q34.3 | GLT6D1 | C | G | 0.41 | 1.59 (1.36–1.86) | 5.51 × 10−9 | 1.88 | [21] |
| rs4284742 | 19q13.41 | SIGLEC5 | G | A | 0.76 | 1.34 (1.21–1.48) | 1.34 × 10−8 | 0.31 | [22] |
| rs2738058 | 8p23.1 | DEFA1A3 | T | C | 0.43 | 1.28 (1.18–1.38) | 6.78 × 10−10 | 0.35 | [22] |
| rs16870060 | 8q22.3 | MTND1P5 | G | T | 0.91 | 1.36 (1.23–1.51) | 3.69 × 10−9 | 0.28 | [23] |
| rs729876 | 16p13.12 | LOC107984137 | T | C | 0.82 | 1.24 (1.15–1.34) | 9.77 × 10−9 | 0.25 | [23] |
EA, effect allele; NEA, non-effect allele; EAF, effect allele frequency; OR (95% CI), odds ratio (95% confidence interval); PVE, proportion of variance explained.