Table 2.

Studentised residuals and Cook's distances calculated for stroke and coronary artery disease models.

Outcome	Coronary artery disease					Any stroke					Ischaemic stroke
Model	IVW		MR-Egger		MR-PRESSO	IVW		MR-Egger		MR-PRESSO	IVW		MR-Egger		MR-PRESSO
rsID	SR	CD	SR	CD	pGlobal	SR	CD	SR	CD	pGlobal	SR	CD	SR	CD	pGlobal
rs1537415	−1.24	1.55	−0.56	2.88	0.12	−0.08	0.01	−0.39	1.44	0.83	−1.11	1.25	0.80	4.93	0.77
rs4284742	−0.28	0.02	−0.50	0.04		0.44	0.04	0.39	0.03		0.06	<0.01	−0.28	0.01
rs2738058	2.32	0.48	1.50	0.56		1.37	0.31	1.80	0.69		2.94	0.61	1.88	0.72
rs16870060	0.92	0.08	0.78	0.04		−0.66	0.05	−0.53	0.02		−0.89	0.08	−1.72	0.09
rs729876	−0.51	0.03	−1.70	0.48		−1.93	0.18	−2.33	0.60		0.42	0.02	−0.40	0.06
Outcome	Large artery stroke					Cardioembolic stroke					Small vessel stroke
Model	IVW		MR-Egger		MR-PRESSO	IVW		MR-Egger		MR-PRESSO	IVW		MR-Egger		MR-PRESSO
rsID	SR	CD	SR	CD	pGlobal	SR	CD	SR	CD	pGlobal	SR	CD	SR	CD	pGlobal
rs1537415	−2.34	2.76	−3.42	17.59	0.50	−1.37	1.72	4.32	19.31	0.79	0.28	0.11	0.85	5.59	0.53
rs4284742	0.73	0.11	0.48	0.04		−0.04	<0.01	−0.71	0.07		−4.47	0.64	−5.34	0.35
rs2738058	0.46	0.06	−0.11	0.01		1.33	0.30	0.42	0.10		1.04	0.22	1.05	0.41
rs16870060	1.85	0.18	2.01	0.10		−0.56	0.03	−1.86	0.10		0.33	0.01	0.27	<0.01
rs729876	−0.22	0.01	−1.09	0.29		1.58	0.14	0.80	0.19		0.10	<0.01	0.06	<0.01

IVW, inverse-variance weighted; SR, studentised residual; CD, Cook's distance; p_Global, p-value from MR-PRESSO global test.