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. 2020 Sep 27;6(1):dvaa010. doi: 10.1093/eep/dvaa010

Table 1:

Differentially methylated F1 genes involved in reproduction

Gene symbol Gene name DMRs DMSs
Reproduction
General
 adcyap1r1aa,b Adenylate cyclase activating polypeptide 1a (pituitary) receptor type I 4 ↑ 1 ↓
 cftra,b CF transmembrane conductance regulator 2 ↑ 1 ↑
 csf1raa Colony stimulating factor 1 receptor, a 2 ↑, 1 ↓ 1 ↓
 ptenba Phosphatase and tensin homolog b 2 ↑ 0
 gata4a GATA-binding protein 4 6 ↓ 0
 fshra,b Follicle stimulating hormone receptor 2 ↑, 1 ↓ 1 ↑, 2 ↓
 inhbaaa Inhibin subunit beta Aa 3 ↓ 0
 inhbaba,b Inhibin subunit beta Ab 4 ↑, 2 ↓ 1 ↑
 inhbba Inhibin subunit beta Bb 2 ↑ 0
Sexual differentiation
 zfpm2aa,b Zinc finger protein, FOG family member 2a 6 ↓ 2 ↓
 zfpm2ba Zinc finger protein, FOG family member 2b 3 ↑ 0
 sox9aa,b SRY-box transcription factor 9a 1 ↑, 2 ↓ 1 ↓
 sox9ba SRY-box transcription factor 9b 1 ↑ 0
 wnt4ba Wingless-type MMTV integration site family, member 4b 2 ↓ 0
 nr0b1a,b Nuclear receptor subfamily 0, group B, member 1 1 ↓ 1 ↓
Spermatogenesis
 dhx36a,b DEAH (Asp-Glu-Ala-His) box polypeptide 36 2 ↑, 6 ↓ 4 ↑, 8 ↓
 m1apa,b Meiosis 1-associated protein 1 ↑, 2 ↓ 1 ↑, 1 ↓
 fmr1a,b FMRP translational regulator 1 10 ↑, 22 ↓ 12 ↑, 15 ↓
 brip1a BRCA1 interacting protein C-terminal helicase 1 6 ↓ 0
 cadm1aa,b Cell adhesion molecule 1a 9 ↑, 1 ↓ 1 ↑
 cadm1ba Cell adhesion molecule 1b 2 ↑ 0
 dazla Deleted in azoospermia-like 2 ↓ 0
 dzip1a DAZ interacting zinc finger protein 1 2 ↑ 0
 cx43a Connexin 43 1 ↑, 1 ↓ 0
 hook1a Hook microtubule-tethering protein 1 2 ↑, 1 ↓ 0
 hsf2a Heat shock transcription factor 2 1 ↑, 1 ↓ 0
 pdgfaba Platelet-derived growth factor alpha polypeptide b 3 ↑ 0
 piwil2a Piwi-like RNA-mediated gene silencing 2 2 ↓ 0
 sbf1a SET-binding factor 1 2 ↑ 0
 dnaja1a DnaJ heat shock protein family (Hsp40) member A1 1 ↑, 2 ↓ 0
 elavl1a ELAV like RNA-binding protein 1 3 ↓ 0
 jam3ba Junctional adhesion molecule 3b 1 ↑, 3 ↓ 0
 pacrga PARK2 co-regulated 4 ↓ 0
 prlrba Prolactin receptor b 2 ↓ 0
 gpx4ba,b Glutathione peroxidase 4b 1 ↓ 1 ↓
 psme4ba,b Proteasome activator subunit 4b 1 ↑, 1 ↓ 1 ↑
 cnr1a,b Cannabinoid receptor 1 1 ↓ 1 ↓
 rfx2a,b Regulator factor X, 2 2 ↓ 2 ↓
 brdta Bromodomain, testis-specific 4 ↑ 0
Sertoli cell junction
 cldn11ba Claudin 11b 4 ↑ 0
 cldn7ba Claudin 7b 2 ↓ 0
 mtmr2a Myotubularin-related protein 2 2 ↓ 0
 myo7aaa Myosin 7aa 2 ↑ 0
 tjp2aa Tight junction protein 2a 2 ↑, 2 ↓ 0
 tjp2ba,b Tight junction protein 2b 1 ↓ 1 ↓
 itgb1aa Integrin, beta 1a 4 ↓ 0
 limk1aa LIM domain kinase 1a 2 ↑ 0
 tgfb2a Transforming growth factor, beta 2 2 ↓ 0
 klf6aa Kruppel-like factor 6a 5 ↑ 0

Numbers of DMSs and regions are shown with direction of methylation change.

a

Gene is associated with a DMR.

b

Gene is associated with a DMS.