Table 3. Muscle pathologies overview.

CK: creatine kinase.

Muscle pathologies overview
Myalgia	Muscle-discomfort (symptoms): aches, soreness, stiffness, tenderness, or cramps associated with movement. Normal CK level. Myalgia symptoms can be described as similar to what would be experienced with a viral syndrome such as influenza.
Myopathy	Muscle weakness (not due to pain), with or without an elevation in CK level.
Myositis	Muscle inflammation.
Myonecrosis	Elevation in muscle enzymes compared with either baseline CK levels or the upper limit of normal that has been adjusted for age, race, and sex.
Mild myonecrosis	3- to 10-fold elevation in CK.
Moderate myonecrosis	10- to 50-fold elevation in CK.
Severe myonecrosis	50-fold or greater elevation in CK.
Clinical rhabdomyolysis	Myonecrosis + myoglobinuria or myonecrosis + acute renal failure (an increase in serum creatinine of at least 0.5 mg/dL).