Table 5. Dosing of statin summary.
AHA: Ameican Heart Association, ASCVD: atherosclerotic cardiovascular disease, LDL C: low-density lipoprotein C.
| Dosing type | High intensity | Moderate intensity | Low intensity |
| Aim | On average lowers LDL C by more than 50% | On average lowers LDL C between 30% and 50% | On average lowers LDL C less than 30% |
| Choice of drugs | Include atorvastatin (40-80 mg) rosuvastatin (20-40 mg) | Include atorvastatin (10-20mg) rosuvastatin (5-10 mg) | -- |
| Choice of drugs | -- | Simvastatin (20-40), pravastatin (40-80), lovastatin (40 mg), fluvastatin (80 mg), pitavastatin (2-4 mg) | Simvastatin (up to 10 mg), pravastatin (up to 20 mg), lovastatin (up to 20 mg), fluvastatin (up to 40 mg), pitavastatin (up to 1 mg) |
| Indications | |||
| If LDL C > 190 | First choice if age below 75 years | If unable to tolerate high dose or age >75 years | If unable to tolerate a moderate dose |
| If atherosclerosis ACS/stroke/vascular procedures | First choice if age below 75 years | If older than 75 years or unable to tolerate a high dose | Only if unable to tolerate a moderate dose |
| Diabetics | First choice in diabetics with ASCVD risk >7.5% | First choice in diabetics with ASCVD risk less than 7.5% | If unable to tolerate the moderate dose |
| Nondiabetics | First choice if ASCVD risk >7.5% | Optional consider if ASCVD risk <7.5% | If unable to tolerate |