Table 4.
Allergic manifestations and feeding information of third-generation cohort in early childhood
| 3 months | 6 months | 1 year | 2 years | 3 years | 6–7 years | |
|---|---|---|---|---|---|---|
| Ever breastfed | 310/440 (70.5%) | 126/194(65.0%) | 214/302(70.9%) | – | – | – |
| Reported wheeze (ever) | 123/339 (36.4%) | 71/104(36.6%) | 113/302 (37.4%) | 87/202 (43.1%) | 93/180(51.7%) | 37/82(45.1%) |
| Reported chest infections (ever) | 92/441 (20.9%) | 49/187(26.2%) | 97/301 (32.2%) | 79/202 (39.1%) | 93/180 (51.7%) | 44/81(54.3%) |
| Physician diagnosed asthmaa (currentb) | – | – | – | – | 4/180 (2.2%) | 6/82(7.3%) |
| Reported nasal symptoms (ever) | 125/441 (28.3%) | 37/194(19.1%) | 59/303 (19.5%) | 59/202 (29.2%) | 54/180 (30%) | 25/82(30.5%) |
| Reported eczema (ever) | 79/388 (20.4%) | 50/176(28.4) | 98/294 (33.3%) | 73/201 (37.3%) | 72/180 (40%) | 37/82(45.1%) |
| Diagnosed eczema (current) | 45/436 (10.3%) | 29/194 (14.9%) | 41/289 (14.2%) | 38/201 (18.9%) | 45/178 (25.3%) | 15/82(18.3%) |
| Reported food allergy (ever) | 45/441 (10.2%) | 27/193(14.0%) | 57/303 (18.8%) | 30/202 (14.9%) | 21/177(11.9%) | 14/82 (17.1%) |
| Positive skin prick test food and aero-allergens (at each assessment)d | – | – | 39/350 (11.1%) | – | 14/147 (9.5%) | 10/78(12.8%) |
a
Asthma was defined as a yes to physician diagnosed asthma and wheezing during past 12 months of treatment given for asthma.
b
Current denotes: previous 12 months.
c
Current eczema: yes to ever eczema plus itchy rash in past 12 months (except at 3 months) plus typical distribution of rash in the folds and extensor surfaces.
d
Positive skin test was defined as a mean wheal diameter of 3 mm or more to a panel of 12 common allergens.