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Immune regulation by plant polysaccharides through cell surface receptors present on macrophage and dendritic cells; toll-like receptors (TLR-4, TLR-2), Dectin-1, complement receptor 3 (CR3), scavenger receptor (SR) and programmed cell death receptor (PD-1), present on T lymphocytes, Mammalian target of rapamycin (mTOR), TNF receptor-associated factor 6 (TRAF6). IL-1R-associated kinase (IRAK), Spleen tyrosine kinase (Syk), Caspase recruitment domain-containing protein 9 (CARD-9).
