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In-silico models of mRNA secondary structure of cloned native and codon-optimized HERV envelope RNAs. For all RNAs the sequence between the predicted transcription start site and the poly(A) site from the vector pcDNA3.1(+) was used for modeling. Models were calculated using The mfold Web Server (http://unafold.rna.albany.edu/?q=mfold, last accessed data 14.02.2020). For all RNAs the calculated structure with the lowest ΔG is shown.
