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. 2020 Oct 23;17(21):7763. doi: 10.3390/ijerph17217763

Table 3.

Results of generalized estimating equations (GEEs) for the effects of bright light therapy on Beck Depression Inventory-Second Edition (BDI-II) scores and salivary cortisol levels.

Variable Regression Coefficient
(95% CI)
p
BDI-II Score
Group (BLT vs. control) −3.02 (−7.46, 1.46) 0.188
Time
T1 vs. T0 −1.27 (−4.14, 1.61) 0.388
T2 vs. T0 −2.80 (−5.55, −0.05) 0.046
Interaction (group × time)
BLT × T1 vs. control × T0 −7.57 (−11.63, −3.50) <0.001
BLT × T2 vs. control × T0 −6.20 (−10.09, −2.31) 0.002
Salivary cortisol level
Group (BLT vs. control) 3.02 (−4.47, 10.50) 0.430
Time
T1 vs. T0 2.65 (−1.02, 6.32) 0.157
T2 vs. T0 4.08 (−2.56, 10.72) 0.259
Interaction (group × time)
BLT × T1 vs. control × T0 −7.37 (−12.56, −2.18) 0.017
BLT × T2 vs. control × T0 −12.22 (−22.24, −2.20) 0.005

BDI-II: Beck Depression Inventory-Second Edition (BDI-II); BLT: bright light therapy; CI: confidence interval; T0: baseline; T1: 3 weeks; T2: 6 weeks.