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. 2020 Nov 12;15(11):e0242127. doi: 10.1371/journal.pone.0242127

Table 3. Multivariable Cox regression analysis.

Model/Analysis Multivariable Cox regression
Endpoint Discharge Death
Variable Hazard ratio 95% CI p-value Hazard ratio 95% CI p-value
Sex male1 0.68 0.50–0.94 0.020 1.37 0.74–2.54 0.310
Age 65–74 years2 0.63 0.37–1.06 0.079 3.45 1.49–7.98 0.004
Age ≥ 75 years2 0.71 0.49–1.02 0.067 3.56 1.74–7.30 0.001
Hospital-acquired COVID-193 0.73 0.48–1.12 0.155 0.91 0.45–1.84 0.790
Comorbidities present (≥1)4 0.87 0.60–1.25 0.442 1.30 0.61–2.79 0.494
Length of stay5 1.00 0.99–1.01 0.739 0.98 0.94–1.02 0.372
Model/Analysis Fine and Gray model
Endpoint Death
Variable Subdistribution hazard ratio 95% CI p-value
Sex male1 1.90 1.04–3.48 0.03
Age 65–74 years2 4.16 1.82–9.49 <0.001
Age ≥ 75 years2 4.13 2.05–8.32 <0.001
Hospital-acquired COVID-193 1.18 0.60–2.34 0.59
Comorbidities present (≥1)4 1.25 0.59–2.68 0.55
Length of stay5 0.98 0.94–1.03 0.23

1 Reference: female

2 reference: age 0–64 years

3 reference: community-acquired COVID-19

4 reference: no comorbid condition

5 reference: 0 days (Previous length of stay was the time from hospital admission to COVID-19 onset, for patients with community acquired COVID-19, the length of stay was 0 days).