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. 2020 Nov 12;15(11):e0242337. doi: 10.1371/journal.pone.0242337

Table 1. Functions associated with phagocytes and cell proliferation identified in the transcriptome of splenic myeloid cells from hamsters with VL.

Functions p-Value Activation State Activation z-score # Molecules
Cell proliferation of tumor cell lines 2.45E-271 Increased 2.1 278
Hematopoiesis of mononuclear leukocytes 2.58E-41 Increased 2.9 80
Differentiation of mononuclear leukocytes 4.15E-42 Increased 2.8 81
Differentiation of phagocytes 1.52E-21 Increased 2.0 35
Hematopoiesis of phagocytes 4.56E-21 Increased 2.0 30
Infiltration by mononuclear leukocytes 7.52E-21 Increased 2.9 29
Chemotaxis of phagocytes 9.77E-21 Increased 2.7 36
Quantity of hematopoietic progenitor cells 2.86E-36 Increased 2.1 60

p-Value, Fisher’s Exact test to reflect the likelihood that the association between molecules and a given process is due to random chance. Activation state and Z score predicted with IPA.