Table 1. Functions associated with phagocytes and cell proliferation identified in the transcriptome of splenic myeloid cells from hamsters with VL.
Functions | p-Value | Activation State | Activation z-score | # Molecules |
---|---|---|---|---|
Cell proliferation of tumor cell lines | 2.45E-271 | Increased | 2.1 | 278 |
Hematopoiesis of mononuclear leukocytes | 2.58E-41 | Increased | 2.9 | 80 |
Differentiation of mononuclear leukocytes | 4.15E-42 | Increased | 2.8 | 81 |
Differentiation of phagocytes | 1.52E-21 | Increased | 2.0 | 35 |
Hematopoiesis of phagocytes | 4.56E-21 | Increased | 2.0 | 30 |
Infiltration by mononuclear leukocytes | 7.52E-21 | Increased | 2.9 | 29 |
Chemotaxis of phagocytes | 9.77E-21 | Increased | 2.7 | 36 |
Quantity of hematopoietic progenitor cells | 2.86E-36 | Increased | 2.1 | 60 |
p-Value, Fisher’s Exact test to reflect the likelihood that the association between molecules and a given process is due to random chance. Activation state and Z score predicted with IPA.