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. 2020 Jul 4;9(14):e016782. doi: 10.1161/JAHA.120.016782

Table 1.

Demographic Characteristics and Burden of Comorbidities in Patients Hospitalized With Acute Heart Failure

Variable, N (%)

2002–2006

(n=297 112)

2007–2011

(n=4 039 603)

2012–2016

(n=7 469 964)

P Value
Age, y, mean (SD) 73.0 (13.6) 73.6 (14.0) 72.5 (13.8) <0.001
Female 167 152 (56.3) 2 084 589 (51.6) 3 687 864 (49.4) <0.001
Race
White 157 595 (73.3) 2 553 894 (72.7) 5 101 784 (71.4) <0.001
Black 38 362 (17.8) 590 572 (16.8) 1 223 065 (17.1)
Hispanic 12 337 (5.7) 220 037 (6.3) 483 690 (6.8)
Other 6699 (3.2) 149 707 (4.2) 341 180 (4.8)
Comorbidities
Acquired immune deficiency syndrome 286 (0.1) 6305 (0.2) 12 090 (0.2) <0.001
Alcohol abuse 7129 (2.4) 107 309 (2.7) 250 320 (3.4) <0.001
Chronic artery disease 134 908 (44.0) 2 166 795 (51.3) 3 872 004 (51.8) <0.001
Anemia 57 864 (19.9) 1 152 422 (28.5) 2 345 870 (31.4) <0.001
Collagen vascular disease 6357 (2.2) 116 487 (2.9) 251 930 (3.4) <0.001
Chronic pulmonary disease 105 604 (36.2) 1 390 074 (34.4) 2 796 605 (37.4) <0.001
Coagulopathy 11 453 (3.9) 248 375 (6.1) 629 805 (8.4) <0.001
Depression 17 453 (6.0) 361 854 (9.0) 815 905 (10.9) <0.001
Diabetes mellitus 113 242 (38.9) 1 662 937 (41.1) 3 346 645 (44.8) <0.001
Hypertension 154 908 (53.2) 2 614 742 (64.7) 5 178 669 (69.3) <0.001
Liver disease 5142 (1.8) 92 739 (2.3) 262 205 (3.5) <0.001
Lymphoma 2406 (0.8) 40 655 (1.0) 82 030 (1.1) <0.001
Neurological disorders 14 519 (5.0) 293 484 (7.3) 615 720 (8.2) <0.001
Obesity 26 838 (9.2) 584 480 (14.5) 1 619 885 (21.7) <0.001
Peripheral vascular disease 25 999 (8.9) 493 630 (12.2) 1 023 120 (13.7) <0.001
Paralysis 4236 (1.5) 87 401 (2.2) 190 855 (2.6) <0.001
Pulmonary circulation disorders 5460 (1.9) 181 991 (4.5) 337 795 (4.5) <0.001
Solid tumors 4884 (1.7) 73 846 (1.8) 147 185 (2.0) <0.001
Renal failure 60 743 (20.8) 1 473 343 (36.5) 3 095 580 (41.4) <0.001
Peptic ulcer 296 (0.1) 1351 (0.0) 147 185 (2.0) <0.001
Valvular disease 14 160 (4.9) 262 093 (6.5) 557 755 (7.5) <0.001
Hospital location
Rural 40 345 (13.6) 479 686 (11.9) 775 310 (10.4) <0.001
Urban nonteaching 120 745 (40.6) 1 717 713 (42.5) 2 362 484 (31.6)
Urban teaching 136 056 (45.8) 1 842 335 (45.6) 4 332 170 (58.0)
Bed size of the hospital
Small 29 188 (9.8) 444 429 (11.0) 1 200 100 (16.1) <0.001
Medium 82 582 (27.8) 981 131 (24.3) 2 121 964 (28.4)
Large 185 376 (62.4) 2 614 174 (64.7) 4 147 900 (55.5)
Median household income percentile
0–25th 89 755 (31.0) 1 208 602 (30.6) 2 338 315 (31.9) <0.001
26th–50th 71 958 (24.8) 1 059 623 (26.8) 1 937 944 (26.4)
51st–75th 68 443 (23.6) 936 898 (23.7) 1 699 145 (23.2)
76th–100th 59 554 (20.6) 749 978 (19.0) 1 356 950 (18.5)
Primary expected payer
Medicare 229 646 (77.4) 3 104 447 (77.0) 5 677 334 (76.1) <0.001
Medicaid 17 628 (5.9) 263 393 (6.5) 596 800 (8.0) <0.001
Private insurance 37 618 (12.7) 487 046 (12.1) 854 250 (11.5) <0.001
Self‐pay 7471 (2.5) 109 160 (2.7) 189 405 (2.5) <0.001
No charge 617 (0.2) 9107 (0.2) 15 985 (0.2) <0.001