Table 4.
Univariable and Multivariable Logistic Regression Analysis for Factors to Predict Impaired g‐CFR (g‐CFR <1.8)
| Univariable Analysis | Multivariable Analysis | ||||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | ||
| Age, y | 1.05 | 1.00–1.01 | 0.03 | Age, y | 1.06 | 1.01–1.11 | 0.02 |
| Body surface area, m2 | 0.15 | 0.01–1.53 | 0.1 | Log (NT‐proBNP), pg/mL | 1.12 | 0.79–1.59 | 0.4 |
| Killip class II or III | 4.48 | 0.94–21.37 | 0.06 | Mean PCATA | 1.11 | 1.03–1.20 | <0.01 |
| GRACE score | 1.01 | 0.99–1.02 | 0.3 | ||||
| Culprit lesion, LAD or non‐LAD | 0.83 | 0.36–1.93 | 0.7 | ||||
| TIMI flow grade at baseline, 0 or 1 | 1.81 | 0.64–5.10 | 0.3 | ||||
| HDL‐C, mg/dL | 1.03 | 1.00–1.07 | 0.07 | ||||
| Peak CK‐MB, IU/L | 1.00 | 1.00–1.01 | 0.8 | ||||
| eGFR, mL·min−1·1.73m−2 | 0.98 | 0.96–1.01 | 0.2 | ||||
| Log (NT‐proBNP), pg/mL | 1.41 | 1.02–1.95 | 0.04 | ||||
| hs‐CRP, mg/dL | 1.29 | 0.95–1.77 | 0.1 | ||||
| Area at risk mass volume, % | 0.97 | 0.93–1.01 | 0.2 | ||||
| Mean PCATA | 1.09 | 1.01–1.17 | 0.02 | ||||
| RCA PCATA | 1.06 | 1.01–1.13 | 0.03 | ||||
| EF | 0.98 | 0.95–1.02 | 0.4 | ||||
| LGE volume | 1.03 | 0.97–1.10 | 0.3 | ||||
CK‐MB indicates creatine kinase MB; EF, ejection fraction; eGFR, estimated glomerular filtration rate; GRACE, Global Registry of Acute Coronary Events; HDL‐C, high‐density lipoprotein cholesterol; hs‐CRP, high‐sensitivity C‐reactive protein; HR, hazard ratio; LAD, left anterior descending coronary artery; LGE, late gadolinium enhancement; NT‐proBNP: N‐terminal pro‐B‐type natriuretic peptide; PCATA, pericoronary adipose tissue attenuation; RCA, right coronary artery; and TIMI, thrombolysis in myocardial infarction.