Skip to main content
. 2020 Aug 20;9(17):e016625. doi: 10.1161/JAHA.120.016625

Figure 4. Endothelial cell protein markers of oxidative stress and inflammation.

Figure 4

Abundance of nitrotyrosine (NT; oxidative modification of proteins) and expression of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (oxidant‐producing enzyme), manganese superoxide dismutase (MnSOD; antioxidant defenses) and nuclear factor κ B (NFκB; proinflammatory transcription factor) in biopsied venous endothelial cells from midlife/older adults with normal blood pressure (BP; <120/80 mm Hg systolic BP [SBP]/diastolic BP [DBP]) vs above‐normal BP (≥120 mm Hg SBP or ≥80 mm Hg DBP) with example immunofluorescent images of individual endothelial cells below. Data are normalized to human umbilical vein endothelial cell protein expression via immunofluorescence. Box indicates interquartile range and median, whiskers indicate 5th to 95th percentiles. *P<0.05 compared with normal BP.