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. 2020 Aug 1;9(16):e017212. doi: 10.1161/JAHA.120.017212

Figure 1. Incidences (%) of efficacy and safety outcomes (upper left panel), respective effects of NOAC+SAPT regimens vs VKA+DAPT (forest plot in the upper central panel), and number of events prevented or caused per 100 patients treated (upper right panel).

Figure 1

In the bottom left (for MACE) and right (for clinically significant bleeding) panels, the reconstructed Kaplan–Meier curves represent the probability of events in the 2 strategy groups of the population included in all the trials. AUGUSTUS indicates A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart; DAPT, dual antiplatelet therapy; ENTRUST‐AF PCI, Edoxaban Treatment vs Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention; HR, hazard ratio (CI between squared brackets); MACE, major adverse cardiovascular event; NOAC, non–vitamin K antagonist oral anticoagulant; PIONEER AF‐PCI, A Study Exploring Two Strategies of Rivaroxaban and One of Oral Vitamin K Antagonist in Patients With Atrial Fibrillation Who Undergo Percutaneous Coronary Intervention; RE‐DUAL PCI, Evaluation of Dual Therapy With Dabigatran vs Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting; SAPT, single antiplatelet therapy; and VKA, vitamin K antagonist.