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No significant difference was observed in the reduction in BNP concentrations after 12 weeks compared with baseline between the two groups. The ratio of the mean BNP value at week 12 to the baseline value was 0.79 in the luseogliflozin group and 0.87 in the voglibose group (percent change, −9.0% vs −1.9%, ratio of change with luseogliflozin vs voglibose, 0.93; 95% CI, 0.78–1.10; P=0.26). BNP indicates B‐type natriuretic peptide.
