Table 1.

TMAO Withdrawal Study Echocardiographic Measurements

	Control	TMAO	TMAO Withdrawal
Baseline
LV end‐systolic volume, μL	15.8±1.53	22.0±1.63	16.9±2.49
LV end‐diastolic volume, μL	37.0±2.72	44.5±2.36	34.7±3.52
LV ejection fraction, %	67.2±1.29	66.4±2.45	67.8±1.06
LV mass, mg	90.6±1.90	106±7.52	87.46±3.16
17 weeks after TAC
LV end‐systolic volume, μL	40.0±4.37	57.0±5.04a	43.9±6.88b
LV end‐diastolic volume, μL	60.2±5.23	74.3±5.23	69.0±7.98
LV ejection fraction, %	36.3±2.05	24.4±1.36a	45.8±4.43c , d
LV mass, mg	128±7.83	151±9.70	160±9.65c

Data shown as the mean±SEM. LV indicates left ventricular; TAC, transverse aortic constriction; and TMAO, trimethylamine N‐oxide.

^a P<0.01 compared with control group at that time point.

^bP<0.05 compared with TMAO group at that time point.

^c P<0.05 compared with control group at that time point.

^d P<0.01 compared with TMAO group at that time point.