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. 2020 May 11;9(10):e015304. doi: 10.1161/JAHA.119.015304

Table 5.

PRBC Transfusion Is Significantly Associated With Longer Duration of Mechanical Ventilation and Length of Intensive Care Unit Stay

Overall No Transfusion One Transfusion >1 Transfusion P Value P Value 1 vs >1 PRBC Transfusion (Adjusted) P Value 0 vs 1 PRBC Transfusion (Adjusted)
(N=396) (N=73) (N=111) (N=212) (Unadjusted)
Length of mechanical ventilation, d 6 (3, 11) 3 (1, 5) 4 (3, 6) 9 (5, 16) <0.0001 <0.0001 0.43
Length of intensive care unit stay 17 (11, 31) 9 (6, 19) 13 (8, 25) 21 (13, 38) <0.0001 <0.0001 0.059
Infection (wound infection, sepsis) 34 (9%) 5 (7%) 9 (8%) 20 (9%) 0.79 1 1
Death 27 (7%) 2 (3%) 7 (6%) 18 (8%) 0.22 1 0.65

When comparing between strata, those receiving >1 transfusion during the study period had significantly longer intensive care unit length of stay and duration of mechanical ventilation. PRBC indicates packed red blood cell.