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. 2020 May 8;9(10):e015772. doi: 10.1161/JAHA.120.015772

Table 4.

Comparison of Coronary Plaque Features Between Baseline and Follow‐Up CCTA: Subgroup Analysis With Regard to Different Types of Plaque

Baseline Follow‐Up P Value
Non‐calcified plaque (n=73)
Focal Agatston score ··· ··· ···
MLD, mm 2.00±0.47 1.99±0.48 0.83
Diameter stenosis, % 47.00±15.00 43.00±18.00 0.18
Total lesion length, mm 8.50 [6.50–12.50] 8.10 [6.30–12.30] 0.51
TPV, mm3 84.30 [45.50–181.00] 82.20 [44.50–173.00] 0.99
Calcified PV, mm3 ··· ··· ···
No‐calcified PV, mm3 84.30 [45.50–181.00] 82.20 [44.50–173.00] 0.99
LAP 30 (41.00%) 24 (32.90%) 0.25
LAP volume, mm3 0 [0–8.10] 0 [0–5.40] 0.64
Napkin‐ring sign 30 (41.10%) 31 (42.50%) 0.76
Spotty calcification 4 (5.50%) 5 (6.80%) 1.00
Remodeling index 1.08±0.17 1.09±0.17 0.85
ΔCT‐FFR 0.051±0.010 0.035±0.012 0.013
Calcified plaque (n=54)
Focal Agatston score 230.50 [135.00–382.00] 232.50 [137.00–382.00] 1.00
MLD, mm 1.99±0.56 2.00±0.55 0.97
Diameter stenosis, % 48.40±14.00 48.00±15.00 0.97
Total lesion length, mm 19.10 [8.20–27.10] 17.80 [8.50–27.40] 0.92
TPV, mm3 100.45 [59.10–254.60] 99.54 [58.10–255.10] 0.88
Calcified PV, mm3 100.45 [59.10–254.60] 99.54 [58.1–255.10] 0.88
No‐calcified PV, mm3 ··· ··· ···
LAP ··· ··· ···
LAP volume, mm3 ··· ··· ···
Napkin‐ring sign ··· ··· ···
Spotty calcification ··· ··· ···
Remodeling index 1.20±0.20 1.19±0.21 0.96
ΔCT‐FFR 0.048±0.011 0.045±0.012 0.84
Mixed plaque (n=67)
Focal Agatston score 96.00 [52.40–173.50] 97.00 [52.50–177.20] 0.95
MLD, mm 1.91±0.52 1.89±0.52 0.57
Diameter stenosis, % 58.00 [41.00–67.00] 54.00 [40.00–68.00] 0.92
Total lesion length, mm 11.90 [7.14–19.00] 11.20 [6.95–17.80] 0.92
TPV, mm3 181.60 [51.90–353.10] 178.60 [48.90–363.30] 0.99
Calcified PV, mm3 53.50 [20.00–115.40] 54.60 [20.20–115.90] 0.88
No‐calcified PV, mm3 102.00 [31.00–197.60] 101.30 [29.00–209.50] 0.95
LAP 6 (9.00%) 7 (10.40%) 0.77
LAP volume, mm3 0 [0–0] 0 [0–0] 0.79
Napkin‐ring sign 25 (37.30%) 23 (34.30%) 0.71
Spotty calcification 14 (20.90%) 12 (17.90%) 0.66
Remodeling index 1.11±0.21 1.11±0.20 0.98
ΔCT‐FFR 0.063±0.014 0.064±0.016 0.67

CCTA indicates coronary computed tomography angiography; CT, computed tomography; FFR, fractional flow reserve; LAP, Low attenuation plaque; MLD, minimal lumen diameter; PV, plaque volume; and TPV, total plaque volume.