Table 5.
Univariable Cox Regression Analyses: the Effects of Traditional Risk Factors and CAD Characteristics on the Decrease of △CT‐FFR at Follow‐Up CCTA
| Univariate | ||
|---|---|---|
| Unadjusted HR [95% CI] | P Value | |
| Age (per+1 y) | 1.00 [0.98–1.02] | 0.94 |
| Men | 0.94 [0.61–1.46] | 0.79 |
| Diabetes mellitus | 0.71 [0.43–1.17] | 0.18 |
| Dyslipidemia | 0.89 [0.54–1.47] | 0.65 |
| Hypertension | 1.09 [0.71–1.68] | 0.70 |
| Current smoker | 1.56 [0.94–2.61] | 0.09 |
| Family history of CAD | 1.01 [0.72–1.88] | 0.81 |
| LAP(+) at baseline | 1.49 [0.91–2.44] | 0.12 |
| SC(+) at baseline | 0.76 [0.33–1.75] | 0.52 |
| RI at baseline | 0.73 [0.25–2.15] | 0.57 |
| NRS(+) at baseline | 1.17 [0.76–1.82] | 0.49 |
| DS at baseline | 2.47 [0.56–10.93] | 0.23 |
| Agatston calcium score at baseline | 1.00 [0.99–1.01] | 0.92 |
| TPV at baseline | 1.00 [0.99–1.01] | 0.98 |
| Calcified PV at baseline | 1.00 [0.99–1.01] | 0.81 |
| Non‐calcified PV at baseline | 1.00 [0.99–1.01] | 0.78 |
| △CT‐FFR at baseline | 16.33 [0.64–41.35] | 0.09 |
| Plaque type | ||
| Calcified | Reference | ··· |
| Noncalcified | 2.02 [1.12–3.65] | 0.021 |
| Mixed | 1.45 [0.77–2.73] | 0.25 |
CAD indicates coronary artery disease; CCTA, coronary computed tomography angiography; CT, computed tomography; DS, diameter stenosis; FFR, fractional flow reserve; HR, hazard ratio; LAP, low attenuation plaque; NRS, napkin‐ring sign; PV, plaque volume; RI, remodeling index; SC, spotty calcification; and TPV, total plaque volume.