Table 6.
Multivariable Cox Regression Analyses: the Effects of Traditional Risk Factors and CAD Characteristics on the Decrease of △CT‐FFR at Follow‐Up CCTA
| Multivariatea | Multivariateb | |||
|---|---|---|---|---|
| Adjusted HR [95% CI] | P Value | Adjusted HR [95% CI] | P Value | |
| Plaque type | ||||
| Calcified PV | Reference | ··· | Reference | ··· |
| Non‐calcified PV | 2.12 [1.08–4.17] | 0.030 | 2.05 [1.03–4.09] | 0.042 |
| LAP volume | 1.46 [0.74–2.85] | 0.27 | 1.44 [0.74–2.79] | 0.28 |
CAD indicates coronary artery disease; CCTA, coronary computed tomography angiography; CT, computed tomography; FFR, fractional flow reserve; HR, hazard ratio; LAP, low attenuation plaque; and PV, plaque volume.
a
Model 1: adjustment for age, sex, diabetes mellitus, dyslipidemia, hypertension, current smoker, family history of CAD.
b
Model 2: further adjustment for low attenuation plaque, spotty calcification, remodeling index, napkin‐ring sign, diameter stenosis, Agatston calcium score, total plaque volume, calcified plaque volume, non‐calcified plaque volume, △CT‐FFR at baseline.