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. 2020 Nov 2;16(11):e1008334. doi: 10.1371/journal.pcbi.1008334

Fig 5. Regulatory grammar can be learned by ResNet when TFBSs are outside of regulatory grammars and there is heterogeneity in the regulatory sequence categories.

Fig 5

(a) Sum of saliency values for TFBSs in each regulatory grammar across neurons in penultimate layer. (b) Actual labels of simulated regulatory grammar of the TFBS overlaid on t-SNE visualization of TFBS saliency values across neurons. (c) Actual labels of simulated regulatory grammar of the TFBS filtered to only those in the top 10% sum of saliency values across neurons in penultimate layer overlaid on the t-SNE visualization. (d) The sensitivity of predicted labels in (c) across regulatory grammars.