Table 2. Results of bi-rectional MR for the causal relationship between LDL and CAD by various MR methods.

Each cell gives “$\widehat{\beta }$ (SE), p-value”.

Causality	IVW	Egger	Weighted Median	Weighted Mode	RAPS
LDL→CAD	0.51 (0.048),	0.57 (0.070),	0.47 (0.044),	0.54 (0.031),	0.52 (0.023),
	3.6 × 10−26	1.5 × 10−12	3.0 × 10−27	1.0 × 10−31	2.3 × 10−113
CAD→LDL	0.37 (0.14),	0.98 (0.34),	-0.011 (0.017),	-0.020 (0.013),	1.8 (0.12),
	0.0076	0.0063	0.52	0.14	6.9 × 10−54