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. 2020 Oct;41(10):1777–1785. doi: 10.3174/ajnr.A6739

Table 1:

Different origin of the MMA with modifications associated and embryologic explanation

Variations in the Origin of the MMA
Embryologic Implications
Type Associated Changes Embryologic Explanation Embryo Size (mm)
IMA origin Normal anatomy Normal embryology
Basilar artery origin Absence foramen spinosum Anastomosis between SA and trigeminal artery; anastomosis between SA and lateral pontine artery 12
Cavernous ICA origin Absence foramen spinosum Anastomosis between inferolateral trunk and SA 16
Partial persistent SA Absence foramen spinosum; enlargement of the facial canal Regression of the proximal part of the maxillomandibular branch; persistence of the intratympanic segment of the SA 24
Complete persistent SA Enlargement of the facial canal Lack of annexation of the maxillomandibular branch by the ventral pharyngeal artery; persistence of the intratympanic segment of the SA 24
Pseudopetrous ICA origin Absence foramen spinosum; enlargement of the facial canal; absence of the exocranial opening of the carotid canal Agenesis of the first and second segments of the ICA; intratympanic anastomosis between inferior tympanic and caroticotympanic arteries; persistence of the intratympanic segment of the SA 4–5; 24
Cervical ICA origin Absence foramen spinosum; enlargement of the facial canal Intratympanic anastomosis between inferior and superior tympanic arteries; regression of the proximal part of the maxillomandibular branch; persistence of the intratympanic segment of the SA 16; 24
Occipital artery origin Absence foramen spinosum; enlargement of the facial canal No clear explanation
Distal petrous ICA origin Absence foramen spinosum Lack of annexation of the mandibular artery (first aortic arch) by the SA (second aortic arch) 9