FIG 5.

SPLIS appearance and progression of MR imaging findings with age. Sequential MR imaging performed in this infant with SPLIS between 6 weeks and 15 months of age has initially normal findings. At 13 and 15 months of age, there is progressive involvement of the globus pallidus with extensive edema of the caudate, putamen, and thalamus. Diffusivity is increased, and there is a susceptibility effect with a ring of T1- and T2- shortening. The susceptibility-phase images indicate the presence of calcium.