Table 2.
Filter categories | Filter values |
---|---|
Sex | Female, Male |
Age | 18–25, 26–30, 31–35, 36–40, 41–45, 46–50, 51–55, 56–60, 61–65, 66–70, 71–75, 76–80, 81–85, 86–89, ≥90 |
Ethnicity | African, Ashkenazi Jewish, Asian, not specified; Caucasian, Chinese, Filipino, Hispanic, Indian, Japanese, Multiple ethnicities, Native American, Pacific Islander, Unknown* |
Personal Health History | Aneurysm, Angioplasty, Bundle branch or heart block, Bypass, Cardiac arrest, Cardiomegaly, Heart attack, Heart failure, No cardiac events, Stent, Stroke |
Family Health History | Aneurysm, Angioplasty, Bundle branch or heart block, Bypass, Cardiac arrest, Cardiomegaly, Heart attack, Heart failure, Stent, Stroke |
Classification | Benign, Likely Benign, Likely Pathogenic, Pathogenic, VUS |
Gene | ACTA2, ACTC1, APOB, COL3A1, DSC2, DSG2, DSP, FBN1, GLA, KCNH2, KCNQ1, LDLR, LMNA, MYBPC3, MYH7, MYH11, MYL2, MYL3, PCSK9, PKP2, PRKAG2, RYR2, SCN5A, SMAD3, TGFBR1, TGFBR2, TMEM43, TNNI3, TNNT2, TPM1 |
Variant | (Search by HGVS Nomenclature)† |
Zygosity | Heterozygous, Homozygous |
CHARGE-AF Risk Score | Borderline (5%–7.5%), High (>10%), Ineligible‡, Intermediate (7.5%–10%), Low (<5%), Unknown§ |
Framingham Risk Score | Borderline (5%–7.5%), High (>10%), Ineligible‡, Intermediate (7.5%–10%), Low (<5%), Unknown§ |
Polygenic Risk Scoreφ | Calculated, Unknown |
Unknown includes information not reported.
Filter values for ‘Variant’ can only be selected by text typing with auto complete using Human Genome Variation Society (HGVS) nomenclature.
CHARGE-AF ineligible includes individuals <46 or ≥90 years. Framingham ineligibility includes individuals <30 or >74 years.
Unknown includes individuals who did provide enough information to calculate risk scores.
Only displays normalized risk scores between − 3 and 3.