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. 2020 Nov 5;2020:7493281. doi: 10.1155/2020/7493281

Figure 1.

Figure 1

The Herbs-Compounds-TFs/miRNAs-ACE2 networks. (a) The Herbs-Compounds-TFs-ACE2 network was constructed by using Cytoscape 3.7.2. The results revealed that HNF4A could be downregulated by chenodeoxycholic acid, and PPARG could be downregulated by quercetin, genistein, chrysoeriol, wedelolactone, tectorigenin, glabridin, isoarnebin 4, yohimbine, and fisetin. (b) The Herbs-Compounds-miRNAs-ACE2 network was constructed by using Cytoscape 3.7.2. Rg1 and gallic acid could upregulate hsa-miR-2113 and hsa-miR-421, respectively. The red octagons represent herbs, and the orange hexagons represent compounds. The green squares represent TFs, and the pink rectangles represent miRNAs. The blue triangles represent ACE2.