Table 1.
Regulatory relationships between the compounds and TFs/miRNAs of ACE2.
| Compound | Chemical formula | Target | Description |
|---|---|---|---|
| Chenodeoxycholic acid | C24H40O4 | HNF4A | ↓ |
| Genistein | C15H10O5 | PPARG | ↓ |
| Quercetin | C15H10O7 | PPARG | ↓ |
| Chrysoeriol | C16H12O6 | PPARG | ↓ |
| Wedelolactone | C16H10O7 | PPARG | ↓ |
| Tectorigenin | C16H12O6 | PPARG | ↓ |
| Glabridin | C20H20O4 | PPARG | ↓ |
| Isoarnebin 4 | C16H16O5 | PPARG | ↓ |
| Yohimbine | C21H26N2O3 | PPARG | ↓ |
| Fisetin | C15H10O6 | PPARG | ↓ |
| Rg1 | C42H72O14 | hsa-miR-2113 | ↑ |
| Gallic acid | C7H6O5 | hsa-miR-421 | ↑ |
↓: downregulation; ↑: upregulation