Table 1.
Detection rates of both assays according to histological/cytological and hrHPV findings (n = 195)
| GynTect® | QIAsure Methylation Test | P value for comparison of detection rate | |||
|---|---|---|---|---|---|
| Test positive | Detection rate [%] (95% CI) |
Test positive | Detection rate [%] (95% CI) |
||
| hrHPV + | |||||
|
CxCa (n = 2) |
2 | 2/2* | 2 | 2/2* | – |
|
CIS (n = 5) |
5 | 5/5* | 5 | 5/5* | – |
|
CIN3 (n = 35) |
21 |
60.0 (42.1–76.1) |
26 |
74.3 (56.7–87.5) |
0.125 |
|
CIN2 (n = 18) |
6 |
33.3 (13.3–59.0) |
5 |
27.8 (9.7–53.5) |
1.000 |
|
CIN1 (n = 15) |
2 |
13.3 (1.7–40.5) |
4 |
26.7 (7.8–55.1) |
0.500 |
|
no CIN (n = 21) |
6 |
28.6 (11.3–52.2) |
11 |
52.4 (29.8–74.3) |
0.125 |
|
NILM (n = 53) |
3 |
5.7 (1.2–15.7) |
14 |
26.4 (15.3–40.3) |
0.003 |
| hrHPV − | |||||
|
NILM (n = 46) |
1 |
2.2 (0.1–11.5) |
11 |
23.9 (12.6–38.8) |
0.006 |
*Due to the low number of cases we present absolute frequencies for description and omit percentages and statistical comparisons