Table 1.

Extensively studied biomarkers of oxidative stress in patients with leukemia

Biomarkers	Clinical Significance	Pioneer(S)
MDA,TAC	To determine the involvement of OS in AML development and implicate biomarkers of OS in disease diagnosis and prognosis	Tsamesidis et al. 2019
PC,TBARS,LOOH	To evaluate and quantify products of protein carbonylation and lipid peroxidation as valuable indicators for OS and disease progression in CML	Singh et al. 2009
MDA	To estimate MDA concentration as a marker of OS in AML patients receiving treatment	A. Hlavackova et al. 2019
TBARS, PC	To determine oxidative damage from increased OS and decreased antioxidant defense in ALL patients	Battisti et al. 2008

Abbreviations: OS Oxidative stress, MDA Malondialdehyde, TAC Total antioxidant capacity, PC Protein carbonyl, TBARS Thiobarbituric acid reactive substances, LOOH Lipid hydroperoxide, AML Acute myeloid leukemia, CML Chronic myeloid leukemia, ALL Acute lymphoblastic leukemia