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. 2020 Nov 11;12:136. doi: 10.1186/s13195-020-00707-1

Table 2.

Risk of dementia according to continuity of physical activity

Never-PA (n = 99,873) Initiation-PA (n = 45,598) Withdrawal-PA (n = 45,014) Maintenance-PA (n = 56,664)
DAT cases, n (%) 8658 (8.7%) 2888 (6.3%) 3445 (7.7%) 2742 (4.8%)
DAT incidence (per 1000 person-years) 33.25 24.11 29.13 18.77
Unadjusted HR (95% CI)
 DAT 1 (ref) 0.73 (0.70–0.76) 0.88 (0.84–0.91) 0.56 (0.54–0.59)
Adjusted HR* (95% CI)
 DAT 1 (ref) 0.89 (0.85–0.93) 1.00 (0.96–1.04) 0.82 (0.79–0.86)

HR hazard ratio, CI confidence interval, DAT dementia of the Alzheimer type, PA physical activity

*Adjusted for age, gender, hypertension, diabetes mellitus, dyslipidemia, body mass index, history of smoking, and history of alcohol intake