Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 11;8(2):e001237. doi: 10.1136/jitc-2020-001237

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

GSEA showing the top 10 enriched pathways responded to dual anti-PD1/CTLA4 blockade. (A) Bar plots showing the Normalized Enriched Score (NES) of the top 10 upregulated (red) and downregulated (blue) pathways in the peritoneal wash samples from mice treated with dual anti-PD1/CTLA4 blockade relative to IgG control. Representative heatmap showing one of the upregulated pathways (right panel). (B) Bar plots showing the NES of the top 10 upregulated (red) and downregulated (blue) pathways in the tumor samples from mice treated with TALs plus anti-PD1/CTLA4 blockade relative to PBS control. Representative heatmap showing one of the upregulated pathways (right panel). GSEA, gene set enrichment analysis; TALs, tumor-associated leukocytes.