Table 2.
The first 20 genes that have the most negative Δt values (negative Δt means gene expression deviating even more from healthy control after drug treatment and is therefore undesirable). Column headings same as in Table 1
| ID | MeanH | MeanPb | MeanPa | tH~Pb | tH~Pa | Δt |
|---|---|---|---|---|---|---|
| C1orf132 | 18.68247 | 15.5787 | 12.03481 | 1.720729 | 6.150399 | − 4.42967 |
| TTN | 81.53304 | 81.38701 | 43.38747 | 0.00516 | 4.167737 | − 4.16258 |
| MFSD4B | 16.52881 | 14.63438 | 12.18393 | 1.095759 | 5.10132 | − 4.00556 |
| STK39 | 21.85199 | 21.75404 | 17.98743 | 0.039667 | 4.031563 | − 3.9919 |
| PPCDC | 30.06767 | 28.48239 | 23.52954 | 0.490643 | 4.453355 | − 3.96271 |
| RC3H2 | 83.41912 | 76.31473 | 71.25956 | 1.995434 | 5.645152 | − 3.64972 |
| EZH1 | 91.2039 | 85.87195 | 75.65626 | 1.542998 | 5.042697 | − 3.4997 |
| HELLS | 14.71387 | 12.28021 | 10.44332 | 1.345294 | 4.786592 | − 3.4413 |
| ANKRD36B | 18.44703 | 13.77633 | 9.970375 | 1.660923 | 5.047357 | − 3.38643 |
| LINC01138 | 12.93422 | 11.9653 | 9.190063 | 0.536082 | 3.917247 | − 3.38116 |
| CNNM3 | 19.83114 | 19.08763 | 16.34129 | 0.294289 | 3.667048 | − 3.37276 |
| ALG13 | 26.53309 | 26.12448 | 21.08266 | 0.099649 | 3.45059 | − 3.35094 |
| PLA2G6 | 13.24867 | 11.03068 | 9.140276 | 1.493657 | 4.754572 | − 3.26091 |
| ANKRD36 | 41.56848 | 34.32497 | 29.99873 | 1.730452 | 4.990922 | − 3.26047 |
| ANKRD36C | 28.59038 | 25.00426 | 20.63043 | 0.863642 | 4.101587 | − 3.23794 |
| CCNH | 46.21754 | 45.87676 | 39.76174 | 0.100098 | 3.291842 | − 3.19174 |
| LOC105371224 | 17.35159 | 16.08431 | 10.64258 | 0.405861 | 3.488259 | − 3.0824 |
| ABCA5 | 25.68626 | 25.31876 | 21.00044 | 0.15661 | 3.216822 | − 3.06021 |
| DYRK1A | 279.4142 | 273.7788 | 251.3844 | 0.851491 | 3.878661 | − 3.02717 |
| PIGG | 33.24765 | 31.67206 | 26.59577 | 0.390097 | 3.411989 | − 3.02189 |