Table 2.
Probabilities that one drug is better than another regarding responders, in a model without dose level, duration of disease or duration of study
Probability that one drug is better than another given alone | |||||||
---|---|---|---|---|---|---|---|
LD | PRA | ROT | SE | RA | CAB | SA | |
ROP | 0.82 | 0.99 | 1 | 1 | 1 | 1 | 0.94 |
LD | - | 0.93 | 0.94 | 1 | 0.99 | 1 | 0.90 |
PRA | - | - | 0.58 | 0.72 | 0.84 | 0.98 | 0.81 |
ROT | - | - | - | 0.63 | 0.72 | 0.96 | 0.79 |
SE | - | - | - | - | 0.61 | 0.97 | 0.76 |
RA | - | - | - | - | - | 0.92 | 0.73 |
CAB | - | - | - | - | - | - | 0.48 |
Probability that one drug is better than another in combination with levodopa | |||||||
PRA + LD | ROP + LD | ROT + LD | CAB + LD | RA + LD | EN + LD | SA + LD | |
SE + LD | 0.76 | 0.81 | 0.92 | 0.93 | 1 | 1 | 1 |
PRA + LD | - | 0.64 | 0.94 | 0.89 | 1 | 1 | 1 |
ROP + LD | - | - | 0.83 | 0.86 | 1 | 1 | 1 |
ROT + LD | - | - | - | 0.78 | 0.98 | 0.99 | 1 |
CAB + LD | - | - | - | - | 0.56 | 0.76 | 0.94 |
RA + LD | - | - | - | - | - | 0.87 | 1 |
EN + LD | - | - | - | - | - | - | 0.94 |
RA, rasagiline; SA, safinamide; SE, selegiline; CAB, cabergoline; PRA, pramipexole; ROP, ropinirole; ROT, rotigotine; LD, levodopa; EN, entacapone