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. 2020 Jul 24;76(12):1731–1743. doi: 10.1007/s00228-020-02961-6

Table 2.

Probabilities that one drug is better than another regarding responders, in a model without dose level, duration of disease or duration of study

Probability that one drug is better than another given alone
LD PRA ROT SE RA CAB SA
ROP 0.82 0.99 1 1 1 1 0.94
LD - 0.93 0.94 1 0.99 1 0.90
PRA - - 0.58 0.72 0.84 0.98 0.81
ROT - - - 0.63 0.72 0.96 0.79
SE - - - - 0.61 0.97 0.76
RA - - - - - 0.92 0.73
CAB - - - - - - 0.48
Probability that one drug is better than another in combination with levodopa
PRA + LD ROP + LD ROT + LD CAB + LD RA + LD EN + LD SA + LD
SE + LD 0.76 0.81 0.92 0.93 1 1 1
PRA + LD - 0.64 0.94 0.89 1 1 1
ROP + LD - - 0.83 0.86 1 1 1
ROT + LD - - - 0.78 0.98 0.99 1
CAB + LD - - - - 0.56 0.76 0.94
RA + LD - - - - - 0.87 1
EN + LD - - - - - - 0.94

RA, rasagiline; SA, safinamide; SE, selegiline; CAB, cabergoline; PRA, pramipexole; ROP, ropinirole; ROT, rotigotine; LD, levodopa; EN, entacapone