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. 2020 Oct 30;8:586541. doi: 10.3389/fcell.2020.586541

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Copyright © 2020 He, Liu, Huang, Zhuo, Chen, Duan, Tang, Lu and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Olfactory mucosa mesenchymal stem cells (OM-MSCs) alleviated neuronal apoptosis and oxidative stress in ischemia/reperfusion (I/R) rats. (A,B) Apoptosis of ipsilateral brain samples was evaluated by flow cytometry analysis. (C) Representative images of NeuN and TUNEL double immunostaining (scale bar, 40 μm). (D,E) Lipid peroxidation (LPO) and total superoxide dismutase (T-SOD) levels of ipsilateral brain samples were measured by the LPO assay and T-SOD assay kits, respectively. Data are shown as the mean ± SEM (n = 3 animals per group). *p ≤ 0.05, compared with the sham group and ^&p ≤ 0.05, compared with the I/R group.