Table 1.

Particle characterization of NPs.

Formulation	Mean diameter (nm)	Polydispersity index	Zeta potential (mV)	PHL encapsulation efficiency (%)a
PLGA/PHL NPs	211 ± 19	0.14 ± 0.04	− 15.9 ± 2.0	56.5 ± 0.4
DOX@PLGA/PHL NPs	221 ± 11	0.18 ± 0.02	− 8.4 ± 0.7*	42.4 ± 0.3

*p < 0.05, compared with PLGA/PHL NPs.

Data are shown as mean ± standard deviation (SD) (n = 3).

NPs were dispersed in DW at 5 mg/ml.

^a $\text{Encapsulation}\text{efficiency}(\%)=\frac{\text{Actual}\text{amount}\text{of}\text{drug}\text{in}\text{NPs}}{\text{Input}\text{amount}\text{of}\text{drug}\text{in}\text{NPs}}\times 100.$