Table 5.
Crystallographic data collection statistics.
| PDB ID | CysLT1R | CysLT2R | |||||
|---|---|---|---|---|---|---|---|
| 6RZ4 | 6RZ5 | Zafirlukast-P21 | 6RZ6 | 6RZ7 | 6RZ9 | 6RZ8 | |
| Dataset type | SWSX | SFX | SFX | SWSX | SWSX | SWSX | SWSX |
| No. crystals (SFX) or No. minisets (SWSX) | 9 | 28,900 | 17,193 | 74 | 16 | 12 | 8 |
| Cell dimensions | |||||||
| a b c, Å | 59.39 45.89 87.13 | 41.58 68.56 87.37 | 43.86 159.43 73.48 | 69.34 167.95 85.44 | 81.82 142.07 171.21 | 67.67 165.01 82.66 | 78.40 78.40 171.91 |
| α β γ, ° | 90.00 95.69 90.00 | 76.33 76.69 81.19 | 90.00 95.12 90.00 | 90.00 90.00 90.00 | 90.00 90.00 90.00 | 90.00 90.00 90.00 | 90.00 90.00 90.00 |
| Space group | P21 | P1 | P21 | C2221 | F222 | I4 | C2221 |
| Resolution, Å# | 30.0-2.6 (2.67-2.60) | 30.0-2.53 (2.57-2.53) | 30.0-3.5 (3.56-3.50) | 30.0-2.3 (2.36-2.30) | 30.0-2.43 (2.49-2.43) | 30.0-2.5 (2.56-2.50) | 30.0-2.73 (2.80-2.73) |
| Completeness, %# | 99.9 (100.0) | 100.0 (100.0) | 100.0 (100.0) | 99.2 (97.6) | 98.2 (98.0) | 99.9 (100.0) | 94.7 (95.4) |
| Redundancy# | 7.24 (6.86) | 67.6 (31.0) | 128.7 (73.6) | 7.39 (5.80) | 6.15 (6.25) | 12.5 (12.8) | 3.27 (3.35) |
| Rmeas (SWSX) or Rsplit (SFX)# | 0.35 (1.05) | 0.23 (2.80) | 0.16 (2.59) | 0.30 (2.74) | 0.31 (3.33) | 0.24 (5.52) | 0.23 (3.06) |
| I/σ(I)# | 5.59 (1.93) | 2.89 (0.42) | 4.17 (0.46) | 5.75 (0.84) | 5.48 (0.79) | 8.62 (0.67) | 3.72 (0.69) |
| CC*# | 1.00 (0.57) | 0.99 (0.51) | 1.00 (0.61) | 1.00 (0.65) | 1.00 (0.63) | 1.00 (0.50) | 1.00 (0.57) |
#Values in parentheses are for highest-resolution shell.