Skip to main content
. 2020 Oct 30;11:586437. doi: 10.3389/fmicb.2020.586437

FIGURE 1.

FIGURE 1

Microscopic lesion scores (LS) in caecum (A–C), liver (D–F), heart (G–I) and spleen (J–L) of commercial chicken layers infected with a lux-tagged E. coli with or without H. meleagridis. Caeca: normal without pathological changes, LS0 (A); epithelial erosion with infiltration of inflammatory cells in the mucosa, LS1 (B); severe fibrino-necrotic typhlitis with transmural inflammatory cell infiltrate, LS2 (C). Liver: normal without pathological changes, LS0 (D); congestion with periportal infiltration of inflammatory cells (arrow heads), LS1 (E); coalescing necrotizing hepatitis surrounded mostly by lymphocytic cells, LS2 (F). Heart: normal without pathological changes, LS0 (G); cellular infiltrate in the epicardium that extended to the myocardium (arrows), LS1 (H); multifocal interstitial inflammatory infiltrates, mostly granulocytes as indicated by arrow heads, LS2 (I). Spleen: normal without pathological changes LS 0 (J); mild heterophilic infiltration (inset), LS1 (K); severe heterophilic infiltration with lymphoid depletion (inset), LS 2 (L).