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. 2020 Oct 30;11:554089. doi: 10.3389/fneur.2020.554089

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Copyright © 2020 Su and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Brain stimulation to promote stroke recovery. Activation of the injured hemisphere can improve prognosis, and the underlying mechanisms may include the promotion of angiogenesis, mitochondrial integrity and neurotransmission and the inhibition of glial activation, pro-inflammatory mediator secretion and oxidative stress. Healthy hemisphere stimulation could have various influences on stroke recovery. Increased interhemispheric compensation (induced by activated stimulation) or reduced interhemispheric suppression (induced by inhibitory stimulation) may mediate clinical recovery.