Fig. 2.

Interactions of different drugs with Dihydrofolate Reductase (DHFR) after docking with a ethacrynic acid, b Sulphadiazine, c indapamide and d Hydrochlorothiazide are represented. In ball and stick—drug, cartoon—DHFR, stick –residue of DHFR interacting with drug, yellow thick dotted line—hydrogen bond and yellow thin line—non bonded interactions are represented