Table 3.

Odds ratios for poor health states among centenarians with different levels of depression with or without comorbidities^a,b.

	Continuous variable of GDS-15 score	Categorized variables of GDS-15 score			P for trend	P for interaction c
		Normal	MnDD	MDD
With comorbidity
Crude model	1.15 (1.07, 1.25) <0.001	Ref.	2.73 (1.69, 4.43) <0.001	1.75 (0.81, 3.76) 0.153	0.01	0.026
Model 1	1.17 (1.08, 1.28) <0.001	Ref.	2.92 (1.73, 4.93) <0.001	1.93 (0.85, 4.38) 0.118	0.009	0.017
Model 2	1.16 (1.06, 1.27) 0.002	Ref.	2.88 (1.61, 5.14) <0.001	1.56 (0.63, 3.86) 0.340	0.05	0.059
Without comorbidity
Crude model	1.28 (1.21, 1.36) <0.001	Ref.	2.95 (2.11, 4.13) <0.001	6.45 (3.59, 11.59) <0.001	<0.001
Model 1	1.30 (1.22, 1.38) <0.001	Ref.	2.95 (2.09, 4.16) <0.001	7.00 (3.83, 12.80) <0.001	<0.001
Model 2	1.25 (1.17, 1.33) <0.001	Ref.	2.98 (2.03, 4.37) <0.001	5.09 (2.66, 9.72) <0.001	<0.001

^aModel 1: Adjusted for age, gender, ethnicity, marital status, education, and residence type. Model 2: Adjusted for age, gender, ethnicity, marital status, education, and residence type, smoking, drinking, weekly exercise, BMI category, serum albumin, 25-hydroxyvitamin D, C-reactive protein, and comorbidities.

^bData are represented as OR (95% CI) P-value.

^cThe interactions of comorbidities and GDS-15 categories on HRQoL were tested in different models.