. 2020 Oct 30;11:599911. doi: 10.3389/fmicb.2020.599911

TABLE 2A.

Antibacterial activity of lenzimycins A and B (1-2) against a panel of bacterial species.

Number	Strain	Accession number	Remarks	MIC (μg/mL)
				1^a	2^b	AMP^c	NOR^d
1	Bacillus sp.	CCARM 9248		64	8	16	0.12
2	Bacillus cereus	CCARM 0002		128	128	8	1
3	Enterococcus faecalis	CCARM 5171	susceptibl^e	>128	>128	2	1
4	Enterococcus faecalis	CCARM 5025	VRE^e (vanB)	>128	>128	2	2
5	Enterococcus faecium	CCARM 5024	VRE^e (vanA)	0.5	1	32	4
6	Staphylococcus aureus	CCARM 0205	susceptible	32	64	2	1
7	Staphylococcus aureus	CCARM 3855	susceptible	>128	>128	0.25	1
8	Staphylococcus aureus	CCARM 3089	MDR^f	>128	>128	64	128
9	Escherichia coli	CCARM 0230		>128	>128	2	0.03
10	Escherichia coli	CCARM 0237		>128	>128	8	0.5
11	Escherichia coli	CCARM 0235		>128	>128	4	0.06
12	Pseudomonas aeruginosa	CCARM 0219		>128	>128	>128	1
13	Pseudomonas aeruginosa	CCARM 0223		>128	>128	>128	0.5
14	Pseudomonas aeruginosa	CCARM 0225		>128	>128	0.5	0.25
15	Salmonella Typhimurium	CCARM 0240		>128	>128	1	0.06
16	Enterobacter cloacae	CCARM 0252		>128	>128	>128	0.06
17	Enterobacter cloacae	CCARM 0253		>128	>128	1	0.03
18	Klebsiella oxytoca	CCARM 0248		>128	>128	>128	0.03
19	Klebsiella aerogenes	CCARM 0249		>128	>128	2	0.06
20	Escherichia coli	ATCC 25922	QC^g strain	>128	>128	4	0.06
21	Enterococcus faecalis	ATCC 29212	QC^g strain	>128	>128	0.5	2 ∼ 8
22	Enterococcus faecium	ATCC 19434	QC^g strain	16	8	0.5	–
23	Pseudomonas aeruginosa	ATCC 27853	QC^g strain	>128	>128	>128	1 ∼ 4^h
24	Staphylococcus aureus	ATCC 29213	QC^g strain	>128	>128	0.13	0.5 ∼ 2^h
25	Salmonella enteric	ATCC 14028	QC^g strain	128	128	0.13	–
26	Klebsiella pneumoniae	ATCC 10031	QC^g strain	>128	>128	32	–

^a lenzimycin A, ^blenzimycin B, ^cAmpicillin, ^dNorfloxacin, ^eVancomycin-resistant Enterococci, ^fMultiple drug resistance, ^gQuality control, and ^hAcceptable range.