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. 2020 Oct 30;11:596942. doi: 10.3389/fmicb.2020.596942

TABLE 2.

Genes differentially expressed between the VISA and VSSA strains.

Gene_ID log2 fold change RT-qPCR P-value q-value Description
Autolysin-associated genes
SAOUHSC_01524 –6.4203 –2.10 2.86E-11 5.14E-11 Holin-like protein
SAOUHSC_02019 –8.813 –3.12 4.91E-42 2.57E-41 Autolysin
SAOUHSC_00232 –2.8307 –1.39 4.62E-33 2.05E-32 Murein hydrolase regulator LrgA
SAOUHSC_00233 –2.2949 –5.92 3.18E-56 2.01E-55 Anti-holin-like protein LrgB
Cell wall-associated genes
SAOUHSC_00069 –4.6639 –7.32 2.34E-46 1.30E-45 Protein A Spa
SAOUHSC_00229 –2.172 –4.37 0 0 Cell wall biosynthesis protein ScdA
SAOUHSC_01110 2.6238 1.04 1.01E-23 3.58E-23 Fibrinogen-binding protein-like protein
SAOUHSC_02802 4.2929 ND 7.78E-06 1.18E-05 Fibronectin binding protein B
SAOUHSC_01142 –2.4371 –1.34 1.58E-93 1.47E-92 Cell division protein MraZ
SAOUHSC_02963 –2.5384 –2.98 1.45E-17 4.14E-17 Clumping factor B ClfB
SAOUHSC_00544 2.9992 1.50 4.01E-29 1.44E-28 Fibrinogen-binding protein SdrC
SAOUHSC_00545 2.1248 3.96 6.55E-10 1.13E-09 Fibrinogen-binding protein SdrD
SAOUHSC_00114 8.0625 5.83 0 0 Capsular polysaccharide biosynthesis protein Cap5A
SAOUHSC_00115 7.5579 4.93 0 0 Capsular polysaccharide biosynthesis protein Cap5B
SAOUHSC_00116 8.2873 2.34 0 0 Capsular polysaccharide biosynthesis protein Cap8C
SAOUHSC_00117 9.0369 ND 0 0 Capsular polysaccharide biosynthesis protein Cap5D
SAOUHSC_00118 8.9985 2.40 2.08E-88 1.89E-87 Capsular polysaccharide biosynthesis protein Cap5E
SAOUHSC_00119 7.6467 4.69 0 0 Capsular polysaccharide biosynthesis protein Cap8F
SAOUHSC_00126 6.0723 7.23 7.07E-33 2.77E-32 Capsular polysaccharide biosynthesis protein Cap8M
SAOUHSC_00176 –6.6897 –2.98 0 0 Extracellular solute-binding protein
Virulence-associated genes
SAOUHSC_01121 –4.1632 –6.23 0 0 Alpha-hemolysin
SAOUHSC_01942 –4.4034 –2.01 0.00013251 0.00016629 Serine protease SplA
SAOUHSC_01941 –3.2598 –3.29 0.0003595 0.00042238 Serine protease SplB
SAOUHSC_01939 –3.7964 –1.23 2.73E-08 4.78E-08 Serine protease SplC
SAOUHSC_00300 –2.4787 –1.03 2.09E-39 1.04E-38 Lipase
SAOUHSC_02706 –2.0555 –6.25 2.26E-10 4.59E-10 Immunoglobulin G-binding protein Sbi
SAOUHSC_00177 –6.0315 ND 0 0 Maltose ABC transporter permease
Hypothetical protein
SAOUHSC_00179 –6.4487 ND 0 0 Hypothetical protein
SAOUHSC_00180 –6.1303 –0.2.98 0 0 Hypothetical protein
SAOUHSC_00208 –7.054 ND 1.13E-36 4.73E-36 Hypothetical protein
SAOUHSC_00049 –8.0233 –4.92 4.32E-30 1.57E-29 Hypothetical protein
Transcriptional regulators
SAOUHSC_02265 –6.3987 –3.25 1.39E-56 1.35E-55 Accessory gene regulator protein A
SAOUHSC_02261 –2.2777 –4.24 2.80E-35 1.63E-34 Accessory gene regulator protein B
SAOUHSC_02264 –5.9723 –1.53 0 0 Accessory gene regulator protein C
SAOUHSC_00469 1.3894 ND 0 0 Regulatory protein SpoVG
SAOUHSC_02315 2.5381 ND 1.88E-05 2.33E-05 DNA-binding response regulator
SAOUHSC_02862 1.087 3.72 0 0 ATP-dependent Clp protease ATP-binding subunit ClpC

ND, not done.