Table 2.

Factors associated with non-complete renal recovery.

Variable	Univariate analysis		Multivariate analysisa
	OR (95% CI)	P-value	OR (95% CI)	P-value
Age (per 1 year)	1.01 (0.99–1.02)	0.35	1.01 (0.99–1.03)	0.23
Male (vs. Female)	0.70 (0.46–1.08)	0.11	0.66 (0.41–1.08)	0.10
Risk factors for deteriorating kidney function
CKD	2.80 (1.59–4.93)	< 0.001	2.12 (1.10–4.08)	0.02
CHF	2.12 (1.25–3.59)	0.01	1.36 (0.71–2.59)	0.36
CCI	1.18 (1.07–1.29)	0.001	1.15 (1.02–1.28)	0.02
Cause of AKI required CRRT
Sepsis	1.21 (0.77–1.89)	0.40
Surgery	0.93 (0.47–1.83)	0.83
Ischemia	0.87 (0.53–1.43)	0.57
Other	0.96 (0.61–1.52)	0.87
Clinical data
SOFA score	1.08 (0.90–1.19)	0.09	1.10 (0.99–1.22)	0.08
SAPS III	1.02 (0.99–1.05)	0.08	0.99 (0.95–1.03)	0.56
Urine output (per 1 mL/h)	1.05 (0.98–1.12)	0.16	1.06 (0.98–1.14)	0.15
Cr (per 1 mg/dL)	1.11 (1.04–1.18)	0.001	1.11 (1.02–1.20)	0.01
Na (per 1 mEq/L)	0.99 (0.98–1.02)	0.76	1.01 (0.97–1.04)	0.79
K (per 1 mEq/L)	0.98 (0.81–1.20)	0.87	0.78 (0.61–0.99)	0.04
TCO2 (per 1 mmol/L)	0.98 (0.94–1.02)	0.26	0.97 (0.93–1.02)	0.24
Total bilirubin (per 1 mg/dL)	0.96 (0.89–1.04)	0.35	0.99 (0.92–1.07)	0.84
Dyschloremia
Normochloremia	Reference		Reference
Hyperchloremia	2.07 (1.18–3.63)	0.01	2.53 (1.25–5.13)	0.01
Hypochloremia	4.95 (2.77–8.83)	< 0.001	5.12 (2.56–10.23)	< 0.001

CKD, chronic kidney disease; CHF, congestive heart failure; CCI, Charlson comorbidity index; SAPS III, Simplified Acute Physiology Score III; SOFA, Sequential Organ Failure Assessment; CRRT, continuous renal replacement therapy; AKI, acute kidney injury; Cr, creatinine; Na, sodium; K, potassium; TCO₂, total carbon dioxide; OR, odds ratio; CI, confidence interval.

^aAdjusted for age, male, CKD, CHF, CCI, SAPS III score, SOFA, urine output, Cr, Na, K, TCO₂, total bilirubin, hyperchloremia, and hypochloremia.