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. 2020 Nov 12;10:19714. doi: 10.1038/s41598-020-76242-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The phases $ϕ_{i}$ of the glycolytic oscillations of every cell of a population of cell density $ρ = 0.1 %$ (Fig. 1) are plotted on the unit circle (a) during the regime of asynchronous oscillations at $t = 518$ s and (b) during partial synchronisation at $t = 904$ s. The position of the phase of each cell is marked by an asterisk. The vector starting at the origin points to the value of the average phase $Φ$ , and the magnitude of the vector corresponds to the value of the order parameter R (which is (a) $R = 0.14$ and (b) $R = 0.61$ , respectively).