Figure 6.

Voronoi tessellation and segmentation of the cells into spatial clusters. Cell density: 0.1%. (a) In the Voronoi diagram, the positions of the centres of mass of the cells are indicated by green crosses; the cells displaying the highest relative cell area densities ${\sigma }_i>median({\sigma }_i)=2.53$ and those with the shortest intercellular distances $r_{\mathit{ij}}\le 6$ $\mu$m are indicated by blue asterisks and red squares, respectively. (b) Clusters obtained due to segmentation with respect to the (highest) relative cell area density ${\sigma }_i$ and (c) with respect to the (shortest) intercellular distances $r_{\mathit{ij}}$. The field of view had a diameter of 169 $\mu$m and it was binned into $512\times 512$ pixels. Each pixel had a resolution of 0.33 $\mu$m $\times$ 0.33 $\mu$m.