The estrobolome plays a central role in health and disease through the gut microbiota-estrogen axis
Dysbiosis of gut microbiota may induce systemic inflammation and interferes with estrogen metabolism and receptor activation in estrogen-regulated organs, influencing neurocognition, metabolism, and the onset of gynecologic diseases and infertility.
Reprinted from Baker et al.203
Critchley. Menstruation: science and society. Am J Obstet Gynecol 2020.